Anti Chlamydia antibodies IgM

What is Anti Chlamydia antibodies IgM?

Infections with C. trachomatis are often asymptomatic and gradually proceeding, therefore primary infections are often underdiagnosed and infected individuals are not treated insufficient time. After primary infection, IgM, IgA, and IgG antibodies can be detected successively in serum samples.

IgG antibodies are generally considered as markers for any contact with the pathogen irrespective of disease stage. IgM antibodies are characteristic of acute infection, and IgA antibodies indicate the ongoing progression of a chronic infection. All ORGENTEC Anti-chlamydia trachomatis tests use recombinant, type-specific antigens of the serotype-encompassing major outer membrane protein complex (MOMP) of Chlamydia trachomatis.

These are joined by two complementary recombinant antigens, TARP and CPAF, which also react with antigens specific to Chlamydia trachomatis. This increases the sensitivity and specificity of this test relative to conventional ELISAs that are based only on MOMP

Anti-Chlamydia trachomatis IgM

Anti-Chlamydia trachomatis IgM Abs. is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgM antibodies against Chlamydia trachomatis in human serum or plasma. The Anti-Chlamydia trachomatis IgM with rheumatoid factor absorbent test is equipped with the ORGENTEC rheumatoid factor absorbent. This reagent absorbs any rheumatoid factors that may be present during sample processing in the Alegria® instrument, making separate preparation of the serum sample unnecessary.