What is HIV-1 Proviral DNA Detection by RT PCR (Qualitative)?
HIV-1 is a retrovirus that infects cells of the immune system. HIV-1 Proviral DNA Detection by RT PCR (Qualitative) detects HIV-infected lymphocytes using the RT PCR technique. Once it enters a cell, it converts its RNA genome into a proviral DNA that integrates with the DNA of the cell and becomes a part of the host cell DNA. This helps the virus to multiply. The presence of proviral DNA is a key feature of HIV-1 infection and is used as a diagnostic marker for the disease. This test is indicated for testing infants born to HIV-positive mothers, resolving indeterminate western blot results, and detecting early HIV infections after exposure to this virus. This test may also be used to monitor the efficacy of antiretroviral therapy (ART) in patients with established HIV infection. It is important to note that a positive HIV-1 Proviral DNA result indicates HIV-1 infection but it does not provide information about virus replication. It is a qualitative test.

What is HIV?
Human Immunodeficiency Virus (HIV) is a virus that attacks your immune system cells and weakens your ability to fight infections. It spreads through unprotected sex, sharing needles, from mother to newborn during childbirth or breastfeeding, and via blood transfusions. HIV can be managed with antiretroviral therapy (ART), which reduces viral load and prevents transmission. Without treatment, HIV can progress to AIDS, which can be fatal. Avoiding unprotected sex and contaminated needles can help in preventing the infection. What is HIV-1 Proviral DNA Detection by RT PCR (Qualitative) used for? The test is required to be done to detect acute HIV infection. The test involves the detection of HIV proviral DNA in the peripheral blood lymphocytes (that is circulating white blood cells) by PCR assay.

What is HIV-1 Proviral DNA Detection by RT PCR (Qualitative) used for?
The test is required to be done to detect acute HIV infection. The test involves the detection of HIV proviral DNA in the peripheral blood lymphocytes (that is circulating white blood cells) by PCR assay.