What are Lyme disease tests?

Lyme disease is an infection caused by bacteria carried by ticks. Lyme disease tests look for signs of infection in your blood or cerebrospinal fluid.

You can get Lyme disease if an infected tick bites you. Ticks can bite you anywhere on your body, but they usually bite in hard-to-see parts of your body such as the groin, scalp, and armpits. The ticks that cause Lyme disease are tiny, as small as a speck of dirt. So you may not know you have been bitten.

If left untreated, Lyme disease can cause serious health problems affecting your joints, heart, and nervous system. But if diagnosed early, most cases of Lyme disease can be cured after a few weeks of treatment with antibiotics.

Other names: Lyme antibodies detection, Borrelia burgdorferi antibodies test, Borrelia DNA Detection, IgM/IgG by Western Blot, Lyme disease test (CSF), Borrelia antibodies, IgM/IgG

What are they used for?

Lyme disease tests are used to find out if you have a Lyme disease infection.

Why do I need a Lyme disease test?

You may need a Lyme disease test if you have symptoms of infection. The first symptoms of Lyme disease usually show up between three and 30 days after the tick bite. They may include:

• A distinctive skin rash that looks like a bull's eye (a red ring with a clear center)
• Fever
• Chills
• Headache
• Fatigue
• Muscle aches

You may also need a Lyme disease test if you don't have symptoms, but are at risk for infection. You may be at a higher risk if you:

• Recently removed a tick from your body
• Walked in a heavily wooded area, where ticks live, without covering exposed skin or wearing repellent
• Have done either of the above activities and live in or have recently visited the northeast or midwestern areas of the United States, where most Lyme disease cases occur

Lyme disease is most treatable in its early stages, but you may still benefit from testing later on. Symptoms that may show up weeks or months after the tick bite. They may include:

• Severe headache
• Neck stiffness
• Severe joint pain and swelling
• Shooting pains, numbness, or tingling in the hands or feet
• Memory and sleep disorders

What happens during Lyme disease testing?

Lyme disease testing is usually done with your blood or cerebrospinal fluid.
For a Lyme disease blood test:

• A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

If you have symptoms of Lyme disease affecting your nervous systems, such as neck stiffness and numbness in your hands or feet, you may need a test of cerebrospinal fluid (CSF). CSF is a clear liquid found in your brain and spinal cord. During this test, your CSF will be collected through a procedure called a lumbar puncture, also known as a spinal tap. During the procedure:

• You will lie on your side or sit on an exam table.
• A health care provider will clean your back and inject an anesthetic into your skin, so you won't feel pain during the procedure. Your provider may put a numbing cream on your back before this injection.
• Once the area on your back is completely numb, your provider will insert a thin, hollow needle between two vertebrae in your lower spine. Vertebrae are the small backbones that make up your spine.
• Your provider will withdraw a small amount of cerebrospinal fluid for testing. This will take about five minutes.
• You'll need to stay very still while the fluid is being withdrawn.
• Your provider may ask you to lie on your back for an hour or two after the procedure. This may prevent you from getting a headache afterward.

Will I need to do anything to prepare for the test?

You don't need any special preparations for a Lyme disease blood test.
For a lumbar puncture, you may be asked to empty your bladder and bowels before the test.

Are there any risks to Lyme disease tests?

There is very little risk of having a blood test or a lumbar puncture. If you had a blood test, you may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly. If you had a lumbar puncture, you may have pain or tenderness in your back where the needle was inserted. You may also get a headache after the procedure.